Autophagy-associated non-coding RNAs: Unraveling their impact on Parkinson's disease pathogenesis.

Md Sadique HussainEhssan MogladMuhammad AfzalShilpa SharmaDinesh Kumar ChellappanG V SivaprasadMahamedha DeorariWaleed Hassan AlmalkiImran KazmiSami I AlzareaMoyad ShahwanKumud PantHaider AliSachin Kumar SinghKamal DuaVetriselvan Subramaniyan

Published in: CNS neuroscience & therapeutics (2024)

ncRNAs hold significant therapeutic potential for addressing autophagy-related mechanisms in PD. The review highlights innovative therapeutic strategies targeting autophagy-related ncRNAs and discusses the challenges and prospective directions for developing ncRNA-based therapies in clinical practice. The insights from this study underline the importance of ncRNAs in the molecular landscape of PD and their potential in novel treatment approaches.

Keyphrases

cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
clinical practice
drug delivery
risk assessment
combination therapy
climate change
drug induced
smoking cessation