Detection of Atrial Fibrillation Episodes based on 3D Algebraic Relationships between Cardiac Intervals.
Naseha Wafa QammarVaiva ŠiaučiūnaitėVytautas ZabielaAlfonsas VainorasMinvydas RagulskisPublished in: Diagnostics (Basel, Switzerland) (2022)
In this study, the notion of perfect matrices of Lagrange differences is employed to detect atrial fibrillation episodes based on three ECG parameters (JT interval, QRS interval, RR interval). The case study comprised 8 healthy individuals and 7 unhealthy individuals, and the mean and standard deviation of age was 65.84 ± 1.4 years, height was 1.75 ± 0.12 m, and weight was 79.4 ± 0.9 kg. Initially, it was demonstrated that the sensitivity of algebraic relationships between cardiac intervals increases when the dimension of the perfect matrices of Lagrange differences is extended from two to three. The baseline dataset was established using statistical algorithms for classification by means of the developed decision support system. The classification helps to determine whether the new incoming candidate has indications of atrial fibrillation or not. The application of probability distribution graphs and semi-gauge indicator techniques aided in visualizing the categorization of the new candidates. Though the study's data are limited, this work provides a strong foundation for (1) validating the sensitivity of the perfect matrices of Lagrange differences, (2) establishing a robust baseline dataset for supervised classification, and (3) classifying new incoming candidates within the classification framework. From a clinical standpoint, the developed approach assists in the early detection of atrial fibrillation in an individual.
Keyphrases
- atrial fibrillation
- machine learning
- deep learning
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- heart failure
- direct oral anticoagulants
- percutaneous coronary intervention
- left ventricular
- big data
- physical activity
- heart rate
- blood pressure
- coronary artery disease
- heart rate variability
- weight gain
- mitral valve
- living cells
- cardiac resynchronization therapy
- body weight
- sensitive detection
- real time pcr