Pregnancy Outcomes after ZIKV Infection in French Territories in the Americas.
Bruno HoenBruno SchaubAnna L FunkVanessa ArdillonManon BoullardAndré CabiéCaroline CallierGabriel CarlesSylvie CassadouRaymond CésaireMaylis DouineCécile Herrmann-StorckPhilippe KadhelCédric LaouénanYoann MadecAlice MonthieuxMathieu NacherFatiha NajioullahDominique RoussetCatherine RyanKinda SchepersSofia Stegmann-PlanchardBenoît TressièresJean-Luc VoluménieSamson YassinguezoEustase JankyArnaud FontanetPublished in: The New England journal of medicine (2018)
Among pregnant women with symptomatic, PCR-confirmed ZIKV infection, birth defects possibly associated with ZIKV infection were present in 7% of fetuses and infants. Defects occurred more frequently in fetuses and infants whose mothers had been infected early in pregnancy. Longer-term follow-up of infants is required to assess any manifestations not detected at birth. (Funded by the French Ministry of Health and others; ClinicalTrials.gov number, NCT02916732 .).