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The impact of KIR/HLA genes on the risk of developing multibacillary leprosy.

Hugo Vicentin AlvesAmarilis Giaretta de MoraesAfonso Carrasco PepineliBruna Tiaki TiyoQuirino Alves De Lima NetoThais da Silva SantosJorge Juarez Vieira TeixeiraEliane P Ambrosio-AlbuquerqueAna Maria SellJeane Eliete Laguila Visentainer
Published in: PLoS neglected tropical diseases (2019)
Our finding suggests that synergetic associations of activating and inhibitory KIR genes may alter the balance between these receptors and thus interfere in the progression of multibacillary leprosy.
Keyphrases
  • genome wide
  • bioinformatics analysis
  • genome wide identification
  • signaling pathway
  • genome wide analysis
  • dna methylation
  • gene expression