A suitable time point for quantifying the radiochemical purity of 225 Ac-labeled radiopharmaceuticals.
James M KellyAlejandro Amor-CoarasaElizabeth SweeneyJustin J WilsonPatrick W CauseyJohn W BabichPublished in: EJNMMI radiopharmacy and chemistry (2021)
Ac-labeled radiopharmaceuticals can be quantified with acceptable accuracy at least 2 h after radioTLC using various methods of quantifying particle emissions. This time point best balances the need to accurately quantify RCP with the need to safely release the batch as quickly as possible.