Long-Term Follow-Up of Anti-Infliximab Antibodies in Patients With Radiographic Axial Spondyloarthritis: A Marker of Drug Survival and Tapering.
Clarissa Q PimentelAna Cristina de Medeiros RibeiroAndrea Y ShimabucoPercival Degrava Sampaio-BarrosJúlio César B MoraesClaudia G SchainbergCelio Roberto GonçalvesElaine P LeonLéonard De Vinci K KupaSandra G PasotoNádia Emi AikawaClovis A SilvaEloisa S BonfaCarla Gonçalves Schahin SaadPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2024)
This study provided novel data that anti-IFX antibodies is a parameter for reduced tapering survival, reinforcing its detection to guide clinical decision. Additionally, we confirmed in a long-term cohort the anti-IFX antibody association with worse IFX performance and as predictor of the second TNFi good clinical response.