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The effects of denosumab and alendronate on glucocorticoid-induced osteoporosis in patients with glomerular disease: A randomized, controlled trial.

Ken IseriMasayuki IyodaMakoto WatanabeKei MatsumotoDaisuke SanadaTakashi InoueShohei TachibanaTakanori Shibata
Published in: PloS one (2018)
In patients with GIOP, denosumab treatment markedly suppressed bone turnover, which led to a significantly greater increase in LS BMD than with alendronate treatment. These results suggest that denosumab is a therapeutic option for the treatment of GIOP.
Keyphrases
  • bone mineral density
  • postmenopausal women
  • body composition
  • endothelial cells
  • bone regeneration