Abnormal neurovascular control during central and peripheral chemoreceptors stimulation in heart failure patients with preserved ejection fraction.

Yufuko KataokaAllan R K SalesAmanda G RodriguesBeatriz R Goes-SantosLuciene F AzevedoRaphaela V GroehsEdna O SilvaLuciana S SantosPatricia A OliveiraCamila P JordãoAna C M AndradeDenise M L LoboEduardo RondonEdgar Toschi-DiasMaria Janieire N N AlvesDirceu R AlmeidaCarlos Eduardo Negrão

Published in: Clinical autonomic research : official journal of the Clinical Autonomic Research Society (2024)

Peripheral and central chemoreflex controls of MSNA are hypersensitized in patients with HFpEF, which seems to contribute to the increase in MSNA in these patients. In addition, peripheral and central chemoreceptors stimulation in patients with HFpEF causes muscle vasoconstriction.

Keyphrases

ejection fraction
aortic stenosis
heart failure
end stage renal disease
chemotherapy induced
chronic kidney disease
newly diagnosed
skeletal muscle
prognostic factors
cardiac resynchronization therapy