Near Infared Circularly Polarized Luminescence From Water Stable Organic Nanoparticles Containing a Chiral Yb(III) Complex.
Enrico CavalliChiara NardonOliver G WillisFrancesco ZinnaLorenzo Di BariSilvia MizzoniSilvia RuggieriSalvatore C GaglioMassimiliano PerducaClaudio ZacconeAlessandro RomeoFabio PiccinelliPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2022)
We report the first example of very efficient NIR Circularly Polarized Luminescence (CPL) (around 970 nm) in water, obtained thanks to the combined use of a chiral Yb complex and of poly lactic-co-glycolic acid (PLGA) nanoparticles. [YbL(tta) 2 ]CH 3 COO (L=N, N'-bis(2-pyridylmethylidene)-1,2-(R,R+S,S) cyclohexanediamine and tta=2-thenoyltrifluoroacetonate) shows good CPL in organic solvents, because the tta ligands efficiently sensitize Yb NIR luminescence and the readily prepared chiral ligand L endows the complex with the necessary dissymmetry. PLGA nanoparticles incorporate the complex and protect the metal ion from the intrusion of solvent molecules, while ensuring biocompatibility, water solubility and stability to the complex. Hydrophilic NIR-CPL optical probes can find applications in the field of NIR-CPL bio-assays.
Keyphrases
- photodynamic therapy
- drug release
- energy transfer
- ionic liquid
- fluorescence imaging
- quantum dots
- drug delivery
- fluorescent probe
- small molecule
- high throughput
- capillary electrophoresis
- room temperature
- living cells
- water soluble
- liquid chromatography
- light emitting
- walled carbon nanotubes
- simultaneous determination
- solid phase extraction