Multicenter, retrospective, cohort study shows platelet counts predict hepatocellular carcinoma development in patients with nonalcoholic fatty liver disease.
Hideki FujiiMakoto FujiiMichihiro IwakiHideki HayashiHidenori ToyodaSatoshi OedaHideyuki HyogoMiwa KawanakaAsahiro MorishitaKensuke MunekageKazuhito KawataTsubasa TsutsumiKoji SawadaTatsuji MaeshiroHiroshi TobitaYuichi YoshidaMasafumi NaitoAsuka ArakiShingo ArakakiTakumi KawaguchiHidenao NoritakeMasafumi OnoTsutomu MasakiSatoshi YasudaEiichi TomitaMasato YonedaNorifumi KawadaAkihiro TokushigeYoshihiro KamadaHirokazu TakahashiShinichiro UedaShinichi AishimaYoshio SumidaAtsushi NakajimaTakeshi Okanouenull nullPublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2023)
Baseline platelet counts of 192 × 109/L and lower are associated with a higher risk of developing HCC in patients with biopsy-confirmed NAFLD and require active surveillance.