Login / Signup

Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit.

Luregn J SchlapbachLahn StraneyRinaldo BellomoGraeme MacLarenDavid Pilcher
Published in: Intensive care medicine (2017)
SIRS criteria lack specificity to identify children with infection at substantially higher risk of mortality. We demonstrate that adapting Sepsis-3 to age-specific criteria performs better than Sepsis-2-based criteria. Our findings support the translation of Sepsis-3 into paediatric-specific sepsis definitions and highlight the importance of robust paediatric organ dysfunction characterization.
Keyphrases
  • intensive care unit
  • septic shock
  • acute kidney injury
  • young adults
  • emergency department
  • cardiovascular disease
  • cardiovascular events
  • pulmonary embolism
  • risk factors