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Comparison of pharmacokinetics and stability of generics of cefepime, linezolid and piperacillin/tazobactam with their respective originator drugs: an intravenous bioequivalence study in healthy volunteers.

Felix BergmannBeatrix WulkersdorferZoe OesterreicherMartin BauerValentin Al JalaliAlina Nussbaumer-PröllMichael Wölfl-DuchekAnselm JordaEdith LacknerBirgit ReiterThomas StimpflNicolas BallariniFranz KönigMarkus Zeitlinger
Published in: The Journal of antimicrobial chemotherapy (2022)
Compared with their respective originator drugs, generic cefepime, linezolid and piperacillin/tazobactam met the predetermined bioequivalence criteria. All formulations were stable under the storage conditions of their respective comparators.
Keyphrases
  • methicillin resistant staphylococcus aureus
  • gram negative
  • tyrosine kinase
  • staphylococcus aureus
  • multidrug resistant