Respiratory infection risk in primary Sjögren's syndrome complicated with interstitial lung disease: a retrospective study.
Xingyu ZhouHao LiNaidi WangYuebo JinJing HePublished in: Clinical rheumatology (2023)
Among pSS-ILD patients, the most frequent type of ILD was nonspecific interstitial pneumonia. In patients with infection, bacteria were the most common pathogen. Higher levels of ESSDAI, CRP, ESR, and C3 may be correlated with increased infection risk. PAH and reduction of DLCO were identified as independent risk factors. Key Points • ILD and infectious diseases severely affect pSS patient conditions. • Higher levels of ESSDAI, CRP, ESR, and C3 may be correlated with increased infection risks in pSS-ILD. • PAH and reduction of DLCO were identified as independent risk factors for lower respiratory infection.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- risk factors
- case report
- end stage renal disease
- ejection fraction
- prognostic factors
- estrogen receptor
- systemic lupus erythematosus
- disease activity
- polycyclic aromatic hydrocarbons
- candida albicans
- patient reported
- extracorporeal membrane oxygenation