Different Mismatch Concepts for Magnetic Resonance Imaging-Guided Thrombolysis in Unknown Onset Stroke.

Lauranne ScheldemanAnke WoutersFlorent BoutitiePatrick DupontSoren ChristensenBastian ChengMartin EbingerMatthias EndresJochen B FiebachChristian GerloffKeith W MuirNorbert NighoghossianSalvador PedrazaClaus Z SimonsenVincent N ThijsGötz ThomallaRobin Lemmensnull null

Published in: Annals of neurology (2020)

Evaluating both the DWI-FLAIR and PWI-DWI mismatch patterns in patients with unknown time of stroke onset will result in the highest yield of thrombolysis treatment. The treatment benefit of alteplase in patients with a DWI-FLAIR mismatch seems to be driven not merely by the presence of a PWI-DWI mismatch, although this analysis was underpowered. ANN NEUROL 2020;87:931-938.

Keyphrases

diffusion weighted imaging
magnetic resonance imaging
diffusion weighted
acute ischemic stroke
atrial fibrillation
pulmonary embolism
contrast enhanced
computed tomography
combination therapy
replacement therapy
smoking cessation