Appropriate chemopreventive strategy for anti-tubercular therapy related liver injury is unsettled: Results from a systematic review and network meta-analysis.

Anupam Kumar Singh Suhang Verma Praveen Kumar-M Hariom Soni Samvida Sharma Swati Sharma Amol N Patil Navneet Sharma

Published in: Expert review of clinical pharmacology (2020)

N-acetyl cysteine, but not Silymarin/Silibinin, appears to be beneficial in prevention of ATT-DILI. However, the results were limited by the possible risk of bias in included studies, variable definitions of ATT-DILI and limited number and category of patients.

Keyphrases

drug induced
liver injury
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
stem cells
bone marrow
patient reported
cell therapy