In Vivo Regulation of Active Matrix Metalloproteinase-8 (aMMP-8) in Periodontitis: From Transcriptomics to Real-Time Online Diagnostics and Treatment Monitoring.

Nur Rahman Ahmad Seno AjiTülay Yucel-Lindberg Ismo Tapani RäisänenHeidi KuulaMikko T NieminenMaelíosa T C Mc CruddenDyah ListyarifahAnna LundmarkFionnuala T Lundy Shipra GuptaTimo Sorsa

Published in: Diagnostics (Basel, Switzerland) (2024)

-dentilisin in CP gingivae is associated with elevated aMMP-8 levels, potentially contributing to a higher risk of active periodontal tissue collagenolysis and progression of periodontitis. This can be detected by aMMP-8-specific assays and online/real-time aMMP-8 chair-side testing.

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