Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue.
Joachim PfisterDominik SummerChristine RanggerMilos PetrikElisabeth von GuggenbergPaolo MinazziGiovanni B GiovenzanaLuigi AlojClemens DecristoforoPublished in: EJNMMI research (2015)
Overall, AAZTA showed interesting properties as bifunctional chelator for peptides providing mild radiolabelling conditions for both (68)Ga and trivalent metals having advantages over the currently used chelator DOTA. Studies are ongoing to further investigate in vivo targeting properties and stability issues and the influence of spacer length on biodistribution of AAZTA.