Genome-wide gene expression profiling reveals that cuticle alterations and P450 detoxification are associated with deltamethrin and DDT resistance in Anopheles arabiensis populations from Ethiopia.

Eba A SimmaWannes DermauwVasileia BalabanidouSimon SnoeckAstrid BryonRichard M ClarkDelenasaw YewhalawJohn VontasLuc DuchateauThomas Van Leeuwen

Published in: Pest management science (2019)

Our transcriptome sequencing of deltamethrin and DDT resistant An. arabiensis populations from Ethiopia suggests non-target site resistance mechanisms and paves the way for further investigation of the role of cuticle composition in insecticide resistance of malaria vectors. © 2019 Society of Chemical Industry.

Keyphrases

gene expression
genome wide
aedes aegypti
single cell
dna methylation
zika virus
rna seq
genetic diversity
copy number