Optical coherence tomography to measure the progression of myelopathy in adrenoleukodystrophy.
Wouter J C van BallegoijIrene C HuffnagelStephanie I W van de StadtHenry C WeinsteinCarlien A M BennebroekMarc EngelenFrank D VerbraakPublished in: Annals of clinical and translational neurology (2021)
This prospective study demonstrates the potential of OCT-measured retinal neurodegeneration as a surrogate outcome measure for the progression of myelopathy in adrenoleukodystrophy. As differences were small, our findings need to be confirmed with longer follow-up and/or in a larger patient sample.