CircOGDH Is a Penumbra Biomarker and Therapeutic Target in Acute Ischemic Stroke.

Yanfang LiuYufeng LiJiankun ZangTianyuan ZhangYaojie LiZefeng TanDan MaTao ZhangShiyong WangYusheng ZhangLian HuangYousheng WuXuanlin SuZean WengDie DengChi Kwan Tsang Liangxue Lai Dan Lu

Published in: Circulation research (2022)

These results demonstrate that CircOGDH is a potential therapeutic target for regulating ischemia neuronal viability, and is enriched in neuron-derived exosomes in the peripheral blood, exhibiting a predictive biomarker of penumbra in patients with AIS.

Keyphrases

peripheral blood
mesenchymal stem cells
stem cells
human health
risk assessment
bone marrow