Immunological and nutritional predictive factors in patients receiving pembrolizumab for the first-line treatment of non-small cell lung cancer.
Naoki ShijubouToshiyuki SumiYuichi YamadaHisashi NakataYuji MoriHirofumi ChibaPublished in: Journal of cancer research and clinical oncology (2022)
Weight loss is an important negative prognostic factor in patients with NSCLC receiving immunotherapy. Weight maintenance may be important for good ICI treatment efficacy, and future interventions in cancer cachexia are expected to further enhance the treatment efficacy of ICIs.
Keyphrases
- weight loss
- prognostic factors
- small cell lung cancer
- physical activity
- bariatric surgery
- advanced non small cell lung cancer
- body mass index
- papillary thyroid
- type diabetes
- roux en y gastric bypass
- current status
- weight gain
- epidermal growth factor receptor
- gastric bypass
- squamous cell
- body weight
- obese patients
- brain metastases