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Atlas of Cell Repertoire Within Neointimal Lesions Is Metabolically Altered in Hypertensive Rats.

Xiaolei SunJunru WuXiaolin ZhangCheng XieHaijun WeiPengyun LiYan YangHong YuanJingjing CaiQingzhong XiaoJun ChengQingbo Xu
Published in: Hypertension (Dallas, Tex. : 1979) (2024)
This study provides the cell landscape changes of the main aortic cell phenotypic alterations in response to injury and hypertension. Our findings suggest that targeting cellular mitochondrial respiration could be a novel therapeutic for patients with hypertension undergoing vascular angioplasty.
Keyphrases
  • single cell
  • blood pressure
  • cell therapy
  • stem cells
  • aortic valve
  • left ventricular
  • atrial fibrillation
  • pulmonary artery
  • mesenchymal stem cells
  • angiotensin ii
  • smooth muscle