Oral doxycycline prevents skin-associated adverse effects induced by injectable collagenase in a rodent model of capsular contracture around silicone implants.
Yannick F DiehmDimitra Kotsougiani-FischerElena PorstValentin HaugLaura C SiegwartDaniel OverhoffUlrich KneserSebastian FischerPublished in: PloS one (2022)
DOX inhibits CCH and accumulates in the skin. Thereby, DOX can effectively reduce skin laceration after CCH treatment.