Neuromelanin-Sensitive Magnetic Resonance Imaging Changes in the Locus Coeruleus/Subcoeruleus Complex in Patients with Typical and Atypical Parkinsonism.
Alexis NobileauRahul GauravLydia ChougarAlice FaucherRomain ValabrègueGraziella MangoneSmaranda Leu-SemenescuFrançois-Xavier LejeuneJean-Christophe CorvolIsabelle ArnulfMarie VidailhetDavid GrabliBertrand DegosStéphane LehéricyPublished in: Movement disorders : official journal of the Movement Disorder Society (2023)
Neuromelanin signal intensity was reduced in all parkinsonian disorders, except in PD without RBD. The presence of RBD in parkinsonian disorders appears to be associated with lower neuromelanin signal intensity. Furthermore, lower LC/LsC signal changes in PSP could be partly caused by the effect of age. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.