Structural brain abnormalities associated with cognitive impairments in bipolar disorder.

Julian MacoveanuKatherine Olivia FreemanHanne Lie Kjærstad Gitte Moos Knudsen Lars Vedel Kessing Kamilla Woznica Miskowiak

Published in: Acta psychiatrica Scandinavica (2021)

Our findings associate cognitive impairment in bipolar disorder with cerebral white matter deficits, factors which may relate to the observed morphological changes in dorsomedial PFC possibly due to increased neurocognitive effort to maintain symptom stability in these remitted patients.

Keyphrases

bipolar disorder
white matter
major depressive disorder
cognitive impairment
end stage renal disease
newly diagnosed
ejection fraction
traumatic brain injury
peritoneal dialysis
functional connectivity