Our data indicate that higher regional DNAm level at TXNIP was significantly associated with better fasting glucose, HbA1c, and HOMA-IR; and people with higher regional DNAm levels benefited more in insulin and HOMA-IR improvement by taking the average-protein weight-loss diet.
Keyphrases
- weight loss
- glycemic control
- blood glucose
- bariatric surgery
- dna methylation
- type diabetes
- nlrp inflammasome
- roux en y gastric bypass
- gastric bypass
- nk cells
- physical activity
- study protocol
- gene expression
- clinical trial
- phase iii
- genome wide
- insulin resistance
- obese patients
- big data
- weight gain
- amino acid
- data analysis
- body mass index
- small molecule