Persistent alveolar inflammatory response in critically ill patients with COVID-19 is associated with mortality.

Justin de Brabander Leonoor S Boers Robert F J KullbergShiqi ZhangEsther J NossentLeo M A HeunksAlexander P J VlaarPeter I BontaMarcus J SchultzTom van der PollJanWillem DuitmanLieuwe D J Bosnull nullnull nullnull nullnull null

Published in: Thorax (2023)

Patients with COVID-19-related ARDS showed an alveolar inflammatory state related to the innate host response, which was associated with a higher mortality. HDS treatment was associated with decreasing alveolar concentrations of CCL20 and CXCL1.

Keyphrases

inflammatory response
cardiovascular events
immune response
risk factors
oxidative stress
lipopolysaccharide induced
acute respiratory distress syndrome
type diabetes
mechanical ventilation
liver fibrosis