Inflammatory and Hematologic Liver and Platelet (HALP) Scores in Hypothermia-Treated Hypoxic-Ischemic Encephalopathy (HIE).

Handan Hakyemez ToptanKübra Gökçe Tezel Oğuzhan Tezel Ömer AtaçGonca VardarSinem Gülcan KersinEren Özek

Published in: Children (Basel, Switzerland) (2024)

A significant difference in systemic inflammatory markers was found between the HIE and control groups after hypothermia treatment, with significant reductions in the MLR and NLR. These markers, particularly MLR, were significant predictors of adverse clinical outcomes including seizures, PVL, and kidney damage.

Keyphrases

cardiac arrest
oxidative stress
brain injury
early onset
emergency department
combination therapy
adverse drug
replacement therapy