Inconsistency in aortic stenosis severity between CT and echocardiography: prevalence and insights into mechanistic differences using computational fluid dynamics.
Tarun Kumar MittalLuise ReichmuthSanjeev BhattacharyyaManish JainAigul BaltabaevaShelley Rahman HaleySaeed MirsadraeeVasileios PanoulasTito KabirEdward David NicolMiles DalbyQuan LongPublished in: Open heart (2019)
Severe AS by Doppler criteria may be associated with a CT-AVA>1 cm2 in up to a quarter of patients. CFD demonstrates that haemodynamic severity may be exaggerated on Doppler analysis due to high LVOT flow rates, with or without skewed velocity profiles, across the valve orifice. These factors should be considered before making a firm diagnosis of severe AS and evaluation with CT can be helpful.
Keyphrases
- aortic stenosis
- ejection fraction
- computed tomography
- image quality
- dual energy
- aortic valve replacement
- aortic valve
- left ventricular
- contrast enhanced
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- blood flow
- end stage renal disease
- positron emission tomography
- early onset
- newly diagnosed
- magnetic resonance imaging
- risk factors
- coronary artery disease
- magnetic resonance
- peritoneal dialysis
- pulmonary hypertension
- prognostic factors
- patient reported outcomes
- atrial fibrillation