GLP-1 analogs and regional adiposity: A systematic review and meta-analysis.

Ioannis AkoumianakisAnastasios ZagaliotisMaria KonstantarakiTheodosios D Filippatos

Published in: Obesity reviews : an official journal of the International Association for the Study of Obesity (2023)

GLP-1 analog treatment reduces TAT, affecting most studied AT depots, including the pathogenic VAT, EAT, and LAT. GLP-1 analogs may have significant roles in combating metabolic, obesity-associated diseases via reductions of key AT depot volumes.

Keyphrases

insulin resistance
molecular docking
weight gain
metabolic syndrome
type diabetes
high fat diet induced
weight loss
body mass index
adipose tissue
replacement therapy
molecular dynamics simulations