A host-guest ATP responsive strategy for intracellular delivery of phosphopeptides.
Bei-Bei HanYu-Chen PanYan-Mei LiDong-Sheng GuoYong Xiang ChenPublished in: Chemical communications (Cambridge, England) (2021)
We developed a host-guest ATP responsive strategy for efficient intracellular delivery of phosphopeptides, employing a pegylated arginine clustered calix[5]arene nanocarrier system that has great capability of recognizing the phosphate moieties on peptides and penetrating the cell membrane.