The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Salma M WakilCao NguyenNzioka P MuiyaEditha AndresAgnieszka Lykowska-TarnowskaBatoul BazAsma I TahirBrian F MeyerGrant MorahanNduna Dzimiri

Published in: Disease markers (2015)

The present study revealed some unique distribution trends for several variants in Arabs, which displayed partly inverse allelic prevalence compared to other ethnic populations. The results point therefore to the need to verify and ascertain the prevalence of a variant as a prerequisite for engaging it in clinical routine screening in personalized medicine in any given population.

Keyphrases

risk factors
copy number
molecular docking
high throughput
clinical practice
single cell
drug induced
molecular dynamics simulations