Login / Signup

Agreement of aptamer proteomics with standard methods for measuring venous thrombosis biomarkers.

Tariq O FaquihDennis O Mook-KanamoriFrits R RosendaalTrevor BaglinKo Willems van DijkAstrid van Hylckama Vlieg
Published in: Research and practice in thrombosis and haemostasis (2021)
Our results indicate that SomaScan measurement had poor agreement with the standard laboratory measurements. These results may explain why some genome-wide association studies with VTE proteins measured by SomaScan did not confirm previously identified loci. Therefore, SomaScan should be considered with caution in VTE studies.
Keyphrases
  • genome wide association
  • venous thromboembolism
  • case control
  • mass spectrometry
  • gold nanoparticles
  • label free
  • sensitive detection
  • gene expression
  • dna methylation
  • genome wide association study