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Uncovering the Mechanisms of Cinnamic Acid Treating Diabetic Nephropathy Based on Network Pharmacology, Molecular Docking, and Experimental Validation.

Limiao DaiYang HeSiqiang ZhengJiyu TangLanjun FuLi Zhao
Published in: Current computer-aided drug design (2024)
This study revealed the multi-target and multi-pathway characteristics of Cinn against DN. Cinn improved renal pathological damage of DN, which was related to the downregulation of PTEN.
Keyphrases
  • molecular docking
  • diabetic nephropathy
  • cell proliferation
  • molecular dynamics simulations
  • signaling pathway
  • single cell
  • pi k akt