Nonlinear Relation Between Burst Dorsal Root Ganglion Stimulation Amplitude and Behavioral Outcome in an Experimental Model of Painful Diabetic Peripheral Neuropathy.

Glenn FrankenJacques DebetsElbert A J Joosten

Published in: Neuromodulation : journal of the International Neuromodulation Society (2019)

Our findings indicate a nonlinear relationship between Burst-DRGS amplitude and behavioral outcome, with an estimated optimal amplitude of 52% MT. Further optimization and analysis of DRGS driven by insights into the underlying mechanisms related to the various stimulation paradigms is warranted.

Keyphrases

resting state
neuropathic pain
high frequency
functional connectivity
spinal cord
type diabetes
drug induced