Rationale and design of REGINA, a phase II trial of neoadjuvant regorafenib, nivolumab, and short-course radiotherapy in stage II and III rectal cancer.

Giacomo BregniCaroline VandeputteAndrea PrettaChiara SentiElena TrevisiElena Acedo ReinaPashalina KehagiasLiberale GabrielLuigi MorettiMaria Antonietta BaliPieter DemetterPatrick FlamenJavier CarrascoLionel D'HondtKaren GeboesYeter GokburunMarc PeetersMarc Van den EyndeJean-Luc Van LaethemPhilippe VergauweCamille Anastasia ChapotMarc BuyseAmelie DeleporteAlain HendliszFrancesco Sclafani

Published in: Acta oncologica (Stockholm, Sweden) (2021)

Keyphrases

rectal cancer
locally advanced
metastatic colorectal cancer
open label
early stage
squamous cell carcinoma
radiation therapy
radiation induced
placebo controlled