Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration.

Ju-Hyeon Bae Mingi Hong Hyeon-Ju Jeong Hyebeen Kim Sang-Jin Lee Dongryeol Ryu Gyu-Un Bae Sung Chun Cho Young-Sam Lee Robert S Krauss Jong-Sun Kang

Published in: Journal of cachexia, sarcopenia and muscle (2020)

Cdon deficiency in satellite cells causes impaired proliferation of satellite cells and muscle regeneration via aberrant integrin and FGFR signalling.

Keyphrases

induced apoptosis
stem cells
cell cycle arrest
skeletal muscle
signaling pathway
endoplasmic reticulum stress
oxidative stress
cell death
cell therapy
bone marrow
cell proliferation
replacement therapy