Unravelling relationships between obesity, diabetes, and factors related to somatosensory functioning in knee osteoarthritis patients.
Lotte MeertSophie VervullensChristiaan H W HeusdensRob J E M SmeetsMira MeeusMichel G C A M MertensPublished in: Clinical rheumatology (2024)
The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA. However, no significant correlations were found between BMI or HbA1c levels and pain-related outcomes. Future research should focus on longitudinal studies to elucidate the causal relationships and further explore the impact of metabolic factors on pain mechanisms in this patient population. Key Points • The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA.
Keyphrases
- knee osteoarthritis
- chronic pain
- end stage renal disease
- type diabetes
- adipose tissue
- pain management
- transcranial direct current stimulation
- newly diagnosed
- neuropathic pain
- ejection fraction
- chronic kidney disease
- cardiovascular disease
- total knee arthroplasty
- metabolic syndrome
- body mass index
- weight gain
- peritoneal dialysis
- patient reported outcomes
- physical activity
- skeletal muscle
- spinal cord
- case control