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Evaluation of peroxidative stress of cancer cells in vitro by real-time quantification of volatile aldehydes in culture headspace.

Violetta ShestivskaAbigail V RutterJosep Sulé-SusoDavid SmithPatrik Španěl
Published in: Rapid communications in mass spectrometry : RCM (2018)
The results of these experiments demonstrate that peroxidation of cancer cells in vitro can be monitored and evaluated by direct real-time analysis of the volatile aldehydes produced. The combination of adopted methodology potentially has value for the study of other types of VOCs that may be produced by cellular damage.
Keyphrases
  • gas chromatography
  • mass spectrometry
  • oxidative stress
  • solid phase extraction