A dried blood spot-based host genome analysis technique targeting pathological associations with hepatitis B: Development and clinical application in the Cambodian population.
Hiroko SetoyamaNao NishidaShintaro NagashimaKo KoTaiji YamazoeYasuhito TanakaMasashi MizokamiJunko TanakaTatsuya KantoPublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2023)
Based on the DBS system, we clarified the associations of HLA-DPB1 alleles with chronic HBV infection in the Cambodian population for the first time. Because the DBS is a low-cost, durable, transportable and easy-to-handle modality, genetic analysis based on the DBS system is a feasible strategy for getting deeper understanding of HBV epidemiology especially in middle- or low-income countries. This article is protected by copyright. All rights reserved.