Metabolomic signatures of the long-term exposure to air pollution and temperature.
Feiby L NassanRachel S KellyAnna KoshelevaPetros KoutrakisPantel S VokonasJessica A Lasky-SuJoel D SchwartzPublished in: Environmental health : a global access science source (2021)
Using a global untargeted metabolomic approach, we identified several significant metabolites and metabolic pathways associated with long-term exposure to PM2.5, NO2 and temperature. This study is the largest metabolomics study of long-term air pollution, to date, the first study to report a metabolomic signature of long-term temperature exposure, and the first to use ICA in the analysis of both.