Biomarkers of Neurological Outcome After Aneurysmal Subarachnoid Hemorrhage as Early Predictors at Discharge from an Intensive Care Unit.

Jaroslaw KedzioraMalgorzata BurzynskaWaldemar GozdzikAndrzej KüblerKatarzyna KobylinskaBarbara Adamik

Published in: Neurocritical care (2020)

Our findings provide evidence that brain biomarkers such as S100B, NSE, GFAP, and MAPT increase significantly in patients following aSAH. There is a direct relationship between the neurological outcome in the acute treatment phase and the levels of S100B, NSE, and MAPT. The detection of brain-specific biomarkers in conjunction with clinical data may constitute a valuable diagnostic and prognostic tool in the early phase of aSAH treatment.

Keyphrases

intensive care unit
ejection fraction
end stage renal disease
cerebral ischemia
newly diagnosed
white matter
liver failure
prognostic factors
machine learning
extracorporeal membrane oxygenation
quantum dots
aortic dissection
loop mediated isothermal amplification