Anticholinergic Drug Burden and Risk of Incident MCI and Dementia: A Population-based Study.

Ariel GildengersGary P StoehrXinhui RanErin JacobsenEsther TeverovskyChung-Chou H ChangMary Ganguli

Published in: Alzheimer disease and associated disorders (2023)

Among cognitively normal older adults in a population-based sample, anticholinergic drug use is independently associated with subsequently developing MCI, but not dementia. Thus, anticholinergic drug use may influence risk of MCI that is nonprogressive to dementia and potentially be a modifiable risk factor for MCI.

Keyphrases

mild cognitive impairment
cognitive decline
cardiovascular disease
risk factors
emergency department