Antidepressive and antinociceptive effects of ethanolic extract and fruticuline A from Salvia lachnostachys Benth leaves on rodents.
Joyce Alencar Santos RadaiAna Claudia PiccinelliMaira Dante FormagioCristhian Santos OliveiraElide Pereira Dos SantosMaria Élida Alves StefanelloUbirajara Lanza JuniorRodrigo Juliano OliveiraMário Mateus SugizakiCândida Aparecida Leite KassuyaPublished in: PloS one (2017)
SLEE exhibits antihyperalgesic, antidepressant, and antinociceptive effects, and fruticuline A appears to be at least partly responsible for the effects of SLEE. Together, these results demonstrate the antidepressive effects of SLEE and fruticuline A and indicate that both derivatives obtained from S. lachnostachys act against spontaneous neuropathic pain.