Population Pharmacokinetics of Total Rabbit Anti-thymocyte Globulin in Non-obese Adult Patients Undergoing Hematopoietic Cell Transplantation for Hematologic Malignancy.
Takuto TakahashiMasahiro TeramotoKana MatsumotoMutaz M JaberHiroya TamakiKazuhiro IkegameSatoshi YoshiharaKatsuji KaidaPublished in: Clinical pharmacokinetics (2023)
This novel popPK model described the PK of total rATG in the adult HCT patients who received a low-dose rATG conditioning regimen. This model can be used for model-informed precision dosing in the settings with minimal baseline rATG targets (T cells), and early clinical outcomes are of interest.