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The Neuroscience of Nonpharmacological Traditional Chinese Therapy (NTCT) for Major Depressive Disorder: A Systematic Review and Meta-Analysis.

JiaJia YeWai Ming CheungHector Wing Hong Tsang
Published in: Evidence-based complementary and alternative medicine : eCAM (2019)
Acupuncture could effectively relieve depressive syndromes. The clinical effects of acupuncture might be attributable to their influence on three proposed pathways, namely, the hypothalamic-pituitary-adrenal (HPA) axis, the locus coeruleus (LC)-immunity pathway, and the negative feedback loop of the hippocampus. Nevertheless, conclusions are limited due to the small number of studies included and the low-quality of the study designs. In the future, a cross-sectional study is needed to test the proposed plausible pathways. PROSPERO registration number is CRD42017080937.
Keyphrases
  • major depressive disorder
  • bipolar disorder
  • physical activity
  • simultaneous determination
  • risk factors
  • quality improvement
  • mass spectrometry
  • stress induced
  • case control
  • bone marrow
  • cell therapy
  • blood brain barrier