Risk of prostate cancer for men with prior negative biopsies undergoing magnetic resonance imaging compared with biopsy-naive men: A prospective evaluation of the PLUM cohort.
Hiten D PatelElizabeth L KoehneSteven M SheaYasin BhanjiMarielia GerenaAlex GorbonosMarcus L QuekRobert C FlaniganAri GoldbergGopal N GuptaPublished in: Cancer (2021)
Men with a prior negative prostate biopsy had a lower risk of harboring prostate cancer in comparison with those who never had a biopsy. This was true even when patients in each group had similar multiparametric magnetic resonance imaging (mpMRI) findings in terms of Prostate Imaging-Reporting and Data System (PI-RADS)-graded lesions. Decision curve analyses showed that many biopsies could be avoided by the use of the Prospective Loyola University mpMRI prediction models or a PI-RADS 4 cutoff for patients with prior negative biopsies.
Keyphrases
- prostate cancer
- ultrasound guided
- magnetic resonance imaging
- radical prostatectomy
- fine needle aspiration
- end stage renal disease
- middle aged
- ejection fraction
- newly diagnosed
- chronic kidney disease
- computed tomography
- high resolution
- contrast enhanced
- decision making
- patient reported outcomes
- photodynamic therapy
- mass spectrometry
- adverse drug
- data analysis