Genomic risk scores for juvenile idiopathic arthritis and its subtypes.
Rodrigo CánovasJoanna CobbMarta BrozynskaJohn David BowesYun R LiSamantha Louise SmithHakon HakonarsonWendy ThomsonJustine A EllisGad AbrahamJane E MunroMichael InouyePublished in: Annals of the rheumatic diseases (2020)
A GRS for JIA has potential to augment clinical JIA diagnosis protocols, prioritising higher-risk individuals for follow-up and treatment. Consistent with JIA heterogeneity, subtype-specific GRSs showed particularly high performance for enthesitis-related and oligoarthritis JIA.