Inhibition of hyperpolarization-activated cyclic nucleotide-gated channels by β-blocker carvedilol.
Ying CaoShujun ChenYemei LiangTing WuJianxin PangShu-Wen LiuPingzheng ZhouPublished in: British journal of pharmacology (2018)
Carvedilol is a negative gating modulator of HCN channels. It represents a novel structure for future drug design of HCN channel inhibitors.