Painful physical symptoms and antidepressant treatment outcome in depression: a systematic review and meta-analysis.

Jia Jia LiuXiao HuangYan-Ping Bao Lin LuPing DongOwen M WolkowitzJohn R KelsoeJie Shi Ya Bin Wei

Published in: Molecular psychiatry (2024)

This study suggests that PPS are negatively associated with the antidepressant treatment outcome in patients with MDD. It is possible that better management in pain conditions when treating depression can benefit the therapeutic effects of antidepressant medication in depressed patients.

Keyphrases

major depressive disorder
end stage renal disease
sleep quality
depressive symptoms
bipolar disorder
ejection fraction
chronic kidney disease
newly diagnosed
chronic pain
healthcare
peritoneal dialysis
prognostic factors
emergency department
patient reported outcomes